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A correction has been published: N Engl J Med 2006;355(5):533.

Editorial
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Volume 353:2807-2809 December 29, 2005 Number 26
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Aromatase Inhibitors — A Triumph of Translational Oncology
Sandra M. Swain, M.D.

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 by The Breast International Group (BIG) 1-98 Collaborative Group
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Great strides have been made in the diagnosis and treatment of early-stage breast cancer, thanks to advances in molecular medicine, interdisciplinary treatment, and rapid electronic communication. Hormonal therapy, the first and most successful targeted therapy for breast cancer, has saved many thousands of lives. Moreover, screening and adjuvant (postoperative) therapy have increased survival among women with breast cancer.1,2 The improvement in survival can be attributed to both adjuvant tamoxifen therapy and adjuvant chemotherapy and has been found in all subgroups of patients regardless of the presence or absence of tumor cells in draining lymph nodes, including women who are premenopausal, . . . [Full Text of this Article]


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From the Breast Cancer Section, Center for Cancer Research, National Cancer Institute, Bethesda, Md.


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