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Case Records of the Massachusetts General Hospital
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Volume 353:287-295 July 21, 2005 Number 3
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Case 22-2005 — An 81-Year-Old Man with Cough, Fever, and Altered Mental Status
Harry Hollander, M.D., Pamela W. Schaefer, M.D., and E. Tessa Hedley-Whyte, M.D.

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Presentation of Case

Dr. Sherry Chou (Neurology): An 81-year-old man was admitted to the Massachusetts General Hospital in September because of fever, chills, productive cough, and diffuse weakness.

Two weeks before admission, a cough developed, with small amounts of yellowish sputum. The patient was treated with azithromycin for five days, without improvement. Five days before admission, amoxicillin was begun. The cough continued to worsen, with increased production of sputum that was tinged with blood. High fevers and chills developed, with progressive anorexia, diffuse weakness, and mild confusion. He was brought to the emergency department and admitted.

A diagnosis of chronic lymphocytic leukemia (CLL) . . . [Full Text of this Article]

Differential Diagnosis

Defining the Neurologic Syndrome

Complications of CLL

Infectious Causes of Encephalomyelitis

Clinical Diagnoses

Dr. Harry Hollander's Diagnosis

Pathological Discussion

Anatomical Diagnoses


Source Information

From the Division of Infectious Diseases, Department of Medicine, University of California at San Francisco, San Francisco (H.H.); the Departments of Radiology (P.W.S.) and Pathology (E.T.H.-W.), Massachusetts General Hospital, Boston; and the Departments of Radiology (P.W.S.) and Pathology (E.T.H.-W.), Harvard Medical School, Boston.


Related Letters:

Case 22-2005: Intravenous Immune Globulin in Chronic Lymphocytic Leukemia
Newcom S. R., Ellman L., Hirsch M., Hollander H.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:1862-1863, Oct 27, 2005. Correspondence

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