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Previous Volume 353:310-312 July 21, 2005 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Many features of cellular programs are tightly controlled by the balancing actions of activation and inhibitory signals. This principle applies in particular to the cells of the immune system, which are regulated by activating and inhibitory cell-surface receptors. Zhu and colleagues¹ have recently described a clever strategy to repress specific allergic reactions by muting the activity of activation receptors.

The first step of the allergic response is the immunization phase, in which innocuous allergens trigger B cells to produce IgE and IgG that react specifically to these allergens. These IgE molecules then bind to high-affinity receptors for IgE (FcRI) . . . [Full Text of this Article]

Source Information

From the Beth Israel Deaconess Medical Center, Harvard University, Boston.

This article has been cited by other articles:

• Huston, D. P. (2006). Update in allergy and immunology.. ANN INTERN MED 145: 454-458 [Full Text]