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Volume 353:317-318 July 21, 2005 Number 3
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Pesticide-like Poisoning from a Prescription Drug

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To the Editor: Acetylcholinesterase inhibitors have long been known for their use as pesticides. Since the 1990s, acetylcholinesterase-inhibiting pharmaceuticals (donepezil, tacrine, galantamine, and rivastigmine) have been used to treat Alzheimer's disease; they are currently being investigated as a treatment for dementia associated with Parkinson's disease in adults1 and with Tourette's syndrome and autistic and attention deficit–hyperactivity disorders in children.2,3 Wider use of this class of medications for a broader variety of disorders increases the possibility of pesticide-like poisoning from a prescribed medication. We report a case of such poisoning.

A healthy 11-month-old girl (weight, 7.5 kg) presented to a pediatric . . . [Full Text of this Article]



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