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Volume 353:420-422 July 28, 2005 Number 4
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Effectiveness of Antimalarial Drugs

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 by Baird, J. K.
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To the Editor: In his review article (April 14 issue), Baird1 states that prescribing "chloroquine . . . in any setting, except one in which its effectiveness has recently been demonstrated, should be considered irresponsible." As physicians who have worked in rural Zambia, where malaria is endemic, we have witnessed the effect of falciparum malaria on children and are sensitive to Baird's concerns. However, adults rarely become severely ill. We think that chloroquine remains an inexpensive, rapid-acting drug with few side effects and that it is effective in most patients.

However, recent policy changes removed chloroquine from our formulary on . . . [Full Text of this Article]


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