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Previous Volume 353:595-603 August 11, 2005 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 63-year-old woman presents with a history of acute low back pain. She had menopause at 44 years of age but never received postmenopausal hormone-replacement therapy. She reports a history of a Colles' fracture at the age of 60 years. Her mother sustained a hip fracture at 70 years of age. Lumbar-spine films reveal a new vertebral fracture. Dual-energy x-ray absorptiometry of . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Overview

Planning an Intervention Strategy

Nonpharmacologic Options

            Physical Activity

Pharmacologic Options

            Antiresorptive Agents

            Postmenopausal Hormone-Replacement Therapy

            Selective Estrogen-Receptor Modulators

            Bisphosphonates

            Calcitonin

            Strontium Ranelate

            Anabolic Agents

            Combination Therapy

Areas of Uncertainty

Guidelines

Summary and Recommendations

Source Information

From St. Joseph Hospital, Maine Center for Osteoporosis Research and Education, Bangor.

Address reprint requests to Dr. Rosen at St. Joseph Hospital, 900 Broadway, Bldg. 2, Bangor, ME 04401, or at rofe@aol.com.

Related Letters:

Postmenopausal Osteoporosis
Chan A. S., Rosen C. J.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:1974-1975, Nov 3, 2005. Correspondence

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