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Previous Volume 353:952-954 September 1, 2005 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Poynter et al. (May 26 issue)¹ reported a 47 percent reduction in the risk of colorectal cancer among long-term statin users (i.e., five years or more), as compared with short-term users or nonstatin users. In contrast, a randomized trial² and meta-analyses³ have found either a slight increase in cancer among statin users or no relation between statins and cancers. Although trials are often limited to comparatively young, low-risk patients and have short follow-up, this difference may result from methodologic limitations in the observational study by Poynter et al.

Long-term statin users tend to be healthier, less physically . . . [Full Text of this Article]

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• Setoguchi, S., Glynn, R. J., Avorn, J., Mogun, H., Schneeweiss, S. (2007). Statins and the Risk of Lung, Breast, and Colorectal Cancer in the Elderly. Circulation 115: 27-33 [Abstract] [Full Text]