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Volume 354:96-97 January 5, 2006 Number 1
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{gamma}-Hydroxybutyric Acid in Hair

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To the Editor: The review (June 30 issue)1 on {gamma}-hydroxybutyric acid (GHB) generated correspondence (Oct. 13 issue),2 which revealed that biochemical genetics laboratories can detect GHB.2 There is an additional detection method worth noting.

When a medicolegal issue is present (e.g., a drug-facilitated crime), finding a hard-to-detect drug can be important.3 GHB has amnesic properties3 and is fully and rapidly metabolized to carbon dioxide and water. Even succinic acid, a product of GHB metabolism, becomes undetectable in urine within hours of ingestion.

However, the GHB in the body of a crime victim is still present, even after it has been . . . [Full Text of this Article]


Related Letters:

{gamma}-Hydroxybutyric Acid
Sass J. O., Superti-Furga A., Ringel E. R., Addolorato G., Gasbarrini G., Zvosec D. L., Smith S. W.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:1632-1633, Oct 13, 2005. Correspondence



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