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Editorial
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Volume 354:1074-1076 March 9, 2006 Number 10
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Hepatitis B — Preventable and Now Treatable
Jay H. Hoofnagle, M.D.

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Chronic infection with hepatitis B virus (HBV) accounts for an enormous burden of disease worldwide, including up to half of all cases of cirrhosis, end-stage liver disease, and hepatocellular carcinoma.1 With the development of a safe and effective vaccine in the early 1980s, hepatitis B became a preventable disease. Routine HBV vaccination of newborns in Taiwan and China, areas of the world with high rates of hepatitis B, was followed by significant declines in rates of chronic hepatitis B and hepatocellular carcinoma.2 In the United States, where the disease is uncommon, the incidence of new cases is currently 75 percent . . . [Full Text of this Article]


Source Information

From the Liver Disease Research Branch, Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Md.


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