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Volume 354:1086-1089 March 9, 2006 Number 10
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Sleep Apnea and Heart Disease

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 by Bradley, T. D.
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 by Yaggi, H. K.
To the Editor: Bradley and colleagues (Nov. 10 issue)1 report that treatment with continuous positive airway pressure (CPAP) in patients with heart failure and central sleep apnea did not affect morbidity and mortality, although several functional measures significantly improved. During the period of their study (the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Failure [CANPAP] trial), the primary event rate (death and cardiac transplantation) fell significantly. As discussed, this improvement was paralleled by a changing pattern of drug therapy for heart failure. Unfortunately, the use of implantable cardioverter–defibrillators and pacemakers for cardiac-resynchronization therapy was . . . [Full Text of this Article]


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