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Previous Volume 354:1096-1097 March 9, 2006 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the discussion of the clinical syndromes of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (the MELAS syndrome), Dickerson et al. (Nov. 24 issue)¹ do not mention L-arginine therapy. This option should be considered in the treatment of patients with stroke-like episodes. Although no randomized trial of L-arginine therapy for the MELAS syndrome has been performed, observational data support its use, particularly in the acute phase of the disorder.^2,3 Improvement has been reported in stroke-like symptoms within 24 hours after the use of this therapy. Improvements in both blood chemistry and magnetic resonance spectroscopy have . . . [Full Text of this Article]

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