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A correction has been published: N Engl J Med 2006;355(7):745.

Perspective
Volume 354:1109-1112 March 16, 2006 Number 11
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The Potential of Human Papillomavirus Vaccines
Robert Steinbrook, M.D.

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The anticipated licensure within the next three months of a vaccine against human papillomavirus (HPV) would represent a major public health advance against cervical cancer and other, less common cancers, including those of the anus, penis, vagina, and vulva. The Food and Drug Administration (FDA) is conducting a six-month priority review of Merck's investigational HPV vaccine and should announce its licensing decision by June 8. Questions remain, however, about the potential behavioral consequences of routinely vaccinating adolescents against a sexually acquired infection, and the public reaction is uncertain.

Genital HPV infection is common, with an estimated 6.2 million new infections . . . [Full Text of this Article]


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Dr. Steinbrook is a national correspondent for the Journal.

An interview with Dr. Douglas Lowy, chief of the Laboratory of Cellular Oncology at the National Cancer Institute, can be heard at www.nejm.org.


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