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Volume 354:1432-1433 March 30, 2006 Number 13
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Case 37-2005: A Man with Cardiac Arrest while Sleeping

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 by Marill, K. A.
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To the Editor: In the Case Records presented in the December 8 issue,1 the statement by the discussant, "the only identified cause of Brugada syndrome is an abnormality in the cardiac sodium channel," as well as the entire discussion, would have been more useful if some additional data had been added. An article on the Online Mendelian Inheritance in Man Web site (www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601144) clearly establishes that this syndrome can also be associated with organic heart disease, as described previously.2,3 The patient whose case was discussed had neither an SCN5A abnormality nor a family history of sudden death. He . . . [Full Text of this Article]




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