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Dr. Brian M. Wolpin (Hematology and Oncology): A 50-year-old man was referred to the cancer center of this hospital because of a painful lytic bone lesion of the right ulna and multiple hepatic masses that had been identified on computed tomography (CT).
Four months earlier, the patient had noted pain and stiffness in the right elbow that was exacerbated by movement. There was no history of trauma. His primary care physician diagnosed a syndrome associated with overuse. A 10-day course of prednisone and a trial of rofecoxib resulted in no improvement over a period of 6 weeks. Two and a
Differential Diagnosis
Dr. Andrew Zhu's Diagnosis
Pathological Discussion
Discussion of Management
Anatomical Diagnosis
Source Information
From the Cancer Center (A.X.Z.) and the Departments of Radiology (D.V.S.) and Pathology (R.P.H.), Massachusetts General Hospital; the Department of Radiation Oncology and the Division of Pediatric Oncology, DanaFarber Cancer Institute, Brigham and Women's Hospital, and Children's Hospital Boston (A.D.D.); and the Departments of Medicine (A.X.Z.), Radiation Oncology and Pediatrics (A.D.D.), Radiology (D.V.S.), and Pathology (R.P.H.), Harvard Medical School all in Boston.
Related Letters:
Case 13-2006: A Man with a Bone Mass and Lesions in the Liver
Schwartz J. D., Hasserjian R. P., Zhu A. X.
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N Engl J Med 2006;
355:422-423, Jul 27, 2006.
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