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Editorial
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Volume 354:1944-1947 May 4, 2006 Number 18
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Treatment of Peripheral Arterial Disease — Extending "Intervention" to "Therapeutic Choice"
Alan T. Hirsch, M.D.

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 by Schillinger, M.
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Lower-extremity peripheral arterial disease is an important manifestation of systemic atherosclerosis that is associated with markedly increased rates of cardiovascular ischemic events and death.1 Although most patients with peripheral arterial disease are asymptomatic, many have claudication, chronic critical limb ischemia, or acute limb ischemia. As a result, peripheral arterial disease considerably impairs functional status and the quality of life, and it is the most important cause of limb amputation. These effects are magnified by the high prevalence of peripheral arterial disease and the lack of provision of timely care.2

The recognition that standards of care for patients with peripheral arterial . . . [Full Text of this Article]


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From the Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, and the Minneapolis Heart Institute Foundation — both in Minneapolis.


Related Letters:

Balloon Angioplasty or Nitinol Stents for Peripheral-Artery Disease
Dalainas I., Nano G., Kashyap A., Anand K. P., Kashyap S., Golledge J., Norman P., Lederman R. J., Desai P., Iyer R., Pyati S., Schillinger M., Minar E., Hirsch A. T.
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N Engl J Med 2006; 355:521-524, Aug 3, 2006. Correspondence

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