Lower-extremity peripheral arterial disease is an importantmanifestation of systemic atherosclerosis that is associatedwith markedly increased rates of cardiovascular ischemic eventsand death.1 Although most patients with peripheral arterialdisease are asymptomatic, many have claudication, chronic criticallimb ischemia, or acute limb ischemia. As a result, peripheralarterial disease considerably impairs functional status andthe quality of life, and it is the most important cause of limbamputation. These effects are magnified by the high prevalenceof peripheral arterial disease and the lack of provision oftimely care.2
The recognition that standards of care for patients with peripheralarterial . . . [Full Text of this Article]
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From the Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, and the Minneapolis Heart Institute Foundation both in Minneapolis.
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