FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 354:1961-1963 May 4, 2006 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear PubMed Citation

To the Editor: Focal segmental glomerulosclerosis recurs in about 30 percent of patients who undergo kidney transplantation for this condition and leads to the nephrotic syndrome and accelerated graft loss.¹ Cyclosporine, cyclophosphamide, plasmapheresis, protein A immunoabsorption, and mycophenolate mofetil have been variably effective.^1,2

We report the case of a seven-year-old boy who presented with immediate recurrence of focal segmental glomerulosclerosis after transplantation that subsequently resolved only after rituximab treatment of a transplantation-related lymphoma that occurred five months after the surgery. This child originally had biopsy-proven primary focal segmental glomerulosclerosis with the nephrotic syndrome. After 4.5 years, he progressed to renal . . . [Full Text of this Article]

This article has been cited by other articles:

• Apeland, T., Hartmann, A. (2008). Rituximab therapy in early recurrent focal segmental sclerosis after renal transplantation. Nephrol Dial Transplant 23: 2091-2094 [Full Text]  
• Coppo, R. (2008). Non-steroidal and non-cytotoxic therapies for nephrotic syndrome. Nephrol Dial Transplant 23: 1793-1796 [Full Text]  
• Deegens, J. K. J., Wetzels, J. F. M. (2008). Rituximab for plasma exchange-dependent recurrent focal segmental glomerulosclerosis after renal transplantation. NDT Plus 1: 85-88 [Full Text]  
• Ahmed, M. S., Wong, C. F. (2008). Rituximab and nephrotic syndrome: a new therapeutic hope?. Nephrol Dial Transplant 23: 11-17 [Full Text]  
• El-Firjani, A., Hoar, S., Karpinski, J., Bell, R., Deschenes, M.-J., Knoll, G. A. (2008). Post-transplant focal segmental glomerulosclerosis refractory to plasmapheresis and rituximab therapy. Nephrol Dial Transplant 23: 425-425 [Full Text]  
• Bagga, A., Sinha, A., Moudgil, A. (2007). Rituximab in Patients with the Steroid-Resistant Nephrotic Syndrome. NEJM 356: 2751-2752 [Full Text]