In the Childhood Asthma Management Program study of school-agedchildren with established mild-to-moderate persistent asthma,twice-daily therapy with inhaled corticosteroids controlledsymptoms of asthma but slightly reduced height growth and didnot improve lung growth or affect the natural course of thedisease.1 In this issue of the Journal, two studies involvingyoung children2,3 test the hypothesis that the natural historyof wheezing in early life may be altered by the administrationof continuous or intermittent doses of inhaled corticosteroidswhen symptoms first occur but when the diagnosis of asthma isstill uncertain. Both groups of authors conclude that inhaled. . . [Full Text of this Article]
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From the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School both in Boston.
Related Letters:
Inhaled Corticosteroids and Children
Köhler D., Haidl P., Dellweg D., Bont L., Kimpen J. L.L., Ermers M. J.J., Baraldi E., Filippone M., Guilbert T., Martinez F. D., Szefler S. J., the Childhood Asthma Research and Education (CARE) Network Steering Committee , Bisgaard H., Gold D. R., Fuhlbrigge A. L.
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N Engl J Med 2006;
355:624-626, Aug 10, 2006.
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