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Previous Volume 354:2075-2076 May 11, 2006 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the article by Lees et al. (Feb. 9 issue)¹ about the Stroke–Acute Ischemic NXY Treatment (SAINT I) trial, the abstract suggests significant reduction of hemorrhagic transformation after receipt of NXY-059, as determined by a post hoc analysis. These data are not associated with the primary or secondary outcomes of the trial, the groups were not powered for the appropriate statistical analysis, and there is a strong possibility of a plausible alternative explanation. Such a comparison is suitable for a future meta-analysis after data from multiple studies with NXY-059 are available and can be pooled together. Presenting . . . [Full Text of this Article]

This article has been cited by other articles:

• Ginsberg, M. D. (2007). Response to Letter by Fisher et al. Stroke 38: e128-e128 [Full Text]  
• Dawson, J., Lees, J. S., Chang, T.-P., Walters, M. R., Ali, M., Davis, S. M., Diener, H.-C., Lees, K. R., for the GAIN and VISTA Investigators, (2007). Association Between Disability Measures and Healthcare Costs After Initial Treatment for Acute Stroke. Stroke 38: 1893-1898 [Abstract] [Full Text]  
• Serebruany, V. L. (2006). Hypokalemia, Cardiac Failure, and Reporting NXY-059 Safety for Acute Stroke. J CARDIOVASC PHARMACOL THER 11: 229-231 [Abstract]