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Previous Volume 354:2287-2288 May 25, 2006 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The findings of the Women's Health Initiative (WHI) trial of calcium and vitamin D supplementation and the risk of colorectal cancer reported by Wactawski-Wende et al. (Feb. 16 issue)¹ are not surprising. The chief problem with the study, in retrospect, is that, as the authors acknowledge, the dose of 400 IU of vitamin D₃ was inadequate to raise blood levels of 25-hydroxyvitamin D to what is now considered a healthful range above 78 nmol per liter (30 ng per milliliter). It is now generally recommended that 1000 IU of vitamin D₃ per day is necessary to attain . . . [Full Text of this Article]

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