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Previous Volume 354:2293-2294 May 25, 2006 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Gruchalla and Pirmohamed (Feb. 9 issue)¹ recommend that before the initiation of cephalosporin therapy, skin testing should be performed for patients with a suspected history of IgE-mediated reactions to penicillins. We would like to add that it is equally important to recognize the potential for cross-reactivity between penicillins and carbapenems. From our experience, this relationship is often not recognized among clinicians. With the emergence of multidrug-resistant bacteria with extended-spectrum beta-lactamases, the use of carbapenems has somewhat expanded beyond the traditional use in only the sickest of patients.

The authors adroitly state that the rate of cross-reactivity of . . . [Full Text of this Article]

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