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Volume 354:2411-2414 June 8, 2006 Number 23
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One Disease, Two Epidemics — AIDS at 25
Kent A. Sepkowitz, M.D.

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Twenty-five years have passed since the first cases of AIDS were recognized. During the first two decades, the epidemiology and clinical presentation of the disease were established, and potent antiviral therapies were developed — for use in patients who could afford them. The progress of the past five years has been less dramatic. Indeed, the most salient change was a widening of the gap between the haves and the have-nots, so that today a single virus is responsible for two distinct public health calamities.

Placed against the backdrop of the global AIDS epidemic, the AIDS-related problems in developed countries seem . . . [Full Text of this Article]


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Dr. Sepkowitz is an infectious-disease specialist at Memorial Sloan-Kettering Cancer Center, New York.

An interactive AIDS timeline is available with the full text of this article at www.nejm.org.


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