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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
A healthy, active 12-year-old boy is in the first percentile for height (133.0 cm [52.4 in.]; 2.25 SD below the mean for age and sex) and in the third percentile for weight (29 kg [64 lb]) (Figure 1). He is the same size as his 10-year-old sister and is the shortest boy in his seventh-grade class. His father's height is
The Clinical Problem
Strategies and Evidence
Evaluation
Growth Hormone Therapy
Gains in Height
Psychosocial Outcomes
Safety Concerns
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Department of Pediatrics, University of Massachusetts Medical School, Worcester.
Address reprint requests to Dr. Lee at the Pediatric Endocrine Division, Department of Pediatrics, University of Massachusetts Medical School, 55 Lake Ave. N., Worcester, MA 01655, or at mary.lee@umassmed.edu.
Related Letters:
Idiopathic Short Stature
Rapaport R., Lee M. M.
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N Engl J Med 2006;
355:1178, Sep 14, 2006.
Correspondence
This article has been cited by other articles:
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