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Clinical Practice
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Volume 354:2576-2582 June 15, 2006 Number 24
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Idiopathic Short Stature
Mary M. Lee, M.D.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A healthy, active 12-year-old boy is in the first percentile for height (133.0 cm [52.4 in.]; 2.25 SD below the mean for age and sex) and in the third percentile for weight (29 kg [64 lb]) (Figure 1). He is the same size as his 10-year-old sister and is the shortest boy in his seventh-grade class. His father's height is . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Evaluation

Growth Hormone Therapy

            Gains in Height

            Psychosocial Outcomes

            Safety Concerns

Areas of Uncertainty

Guidelines

Conclusions and Recommendations


Source Information

From the Department of Pediatrics, University of Massachusetts Medical School, Worcester.

Address reprint requests to Dr. Lee at the Pediatric Endocrine Division, Department of Pediatrics, University of Massachusetts Medical School, 55 Lake Ave. N., Worcester, MA 01655, or at mary.lee@umassmed.edu.


Related Letters:

Idiopathic Short Stature
Rapaport R., Lee M. M.
Extract | Full Text | PDF  
N Engl J Med 2006; 355:1178, Sep 14, 2006. Correspondence

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