To the Editor: Park-Wyllie and colleagues (March 30 issue)1advise avoiding the use of gatifloxacin because of the increasedrisk of dysglycemia, and they suggest using alternative antibiotics,including other fluoroquinolones, that confer little or no increasedrisk of dysglycemia. This suggestion must be questioned. Althoughit appears that the administration of moxifloxacin has no clinicallyrelevant effect on blood glucose homeostasis,2 other fluoroquinolonesmay trigger dysglycemic events, especially in patients withdiabetes who receive sulfonylureas.3 Clinicians should be awareof the possibility of dysglycemic events in patients receivingfluoroquinolones.
Karl P. Ittner, M.D., D.E.A.A. University of Regensburg D-93042 Regensburg, . . . [Full Text of this Article]
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