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Previous Volume 354:2819-2821 June 29, 2006 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In normal adults, the daily production rate of the two biologically active thyroid hormones, tetraiodothyronine (which is better known as thyroxine and has four iodine atoms) and triiodothyronine (which has three), is approximately 100 µg and 30 µg, respectively. All of the thyroxine, but only about 20 percent of the triiodothyronine, is produced by the thyroid gland; the remainder of the triiodothyronine is produced through the extrathyroidal deiodination of thyroxine. A minimum of approximately 70 µg of iodine is therefore needed to produce these two hormones in the thyroid gland each day. But more than that is required, because iodine . . . [Full Text of this Article]

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From the Department of Medicine, Brigham and Women's Hospital, Boston.

Related Letters:

Iodine Nutrition — More Is Better
Pearce E. N., Hollowell J. G. Jr., Morreale de Escobar G., Escobar del Rey F., Utiger R. D.
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N Engl J Med 2006; 355:1500-1501, Oct 5, 2006. Correspondence

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