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Correction to Ashen and Blumenthal, N Engl J Med 353(12):1252-1260 September 22, 2005.

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Volume 354:417-419 January 26, 2006 Number 4
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Low HDL Cholesterol Levels

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 by Ashen, M. D.
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To the Editor: Ashen and Blumenthal (Sept. 22 issue)1 state that caution is recommended with the use of high-dose niacin in patients with diabetes, because niacin may increase glucose levels. However, the Arterial Disease Multiple Intervention Trial (ADMIT)2 showed that niacin can be used safely in patients with diabetes. Levels of glycosylated hemoglobin were unchanged from baseline in patients with diabetes who were assigned to receive niacin therapy. In fact, there were no differences in niacin discontinuation, niacin dosage, or hypoglycemic therapy in patients with diabetes who received niacin, as compared with baseline.

Previous reports of niacin-induced glucose intolerance are . . . [Full Text of this Article]




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