FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 354:483-495 February 2, 2006 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Supplementary Material Purchase this article Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear PubMed Citation

The use of percutaneously introduced prosthetic devices to maintain the luminal integrity of diseased blood vessels was proposed by Dotter and Judkins in 1964,¹ well before the introduction of coronary angioplasty by Grüntzig et al. in 1977.² Palmaz et al. introduced the use of balloon-mounted stents (as used in coronary arteries today) in peripheral arteries in 1985.³ Schatz et al. subsequently modified the Palmaz stent, which led to the development of the first commercially successful stent, the Palmaz–Schatz stent.⁴ Puel and Sigwart were the first to implant a stent in humans in March 1986; they used a self-expanding mesh device. . . . [Full Text of this Article]

Barrier and Bioactive Stent Coatings

Barrier Stent Coatings

Active Stent Coating to Prevent Thrombosis

Drug-Eluting Stents

Successful Drug-Eluting Stents

            Sirolimus-Eluting Stents

            Polymeric Paclitaxel–Eluting Stents

Real-World Experience

Comparative Trials

Investigative Agents

            Zotarolimus

            Everolimus

            Other Agents

Indications for the Use of Coronary Stents

Primary Revascularization after Myocardial Infarction Involving ST-Segment Elevation

            Focal Lesions in Vessels 3.0 mm or More in Diameter

            Focal Lesions in Saphenous-Vein Grafts

            Treatment of Chronic Total Occlusions

            Treatment of Restenosis after Balloon Angioplasty

Segmental Lesions for Which Coronary Stenting is Probably Beneficial

            Long Lesions

            Small Vessels

            Lesions at Bifurcations

Unresolved Issues

            Stenosis of an Unprotected Left Main Coronary Artery

            Multivessel Disease

            Diabetes Mellitus

            In-Stent Restenosis

            Biodegradable Stents

Caveats and Conclusions

Source Information

From the Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands (P.W.S., A.T.L.O.); and the University of Toronto, St. Michael's Hospital, Toronto (M.J.B.K.).

Address reprint requests to Dr. Serruys at the Department of Interventional Cardiology, Thoraxcenter, Erasmus Medical Center, Dr. Molewaterplein 40, 3015 GD Rotterdam, the Netherlands.

Related Letters:

Coronary-Artery Stents
Silverman M. E., Kounis N. G., Kounis G. N., Kouni S. N., Taggart D. P., Serruys P. W., Ong A. T.L.
Extract | Full Text | PDF  
N Engl J Med 2006; 354:2076-2078, May 11, 2006. Correspondence

This article has been cited by other articles:

• Park, S.-J., Kim, Y.-H. (2008). Current Status of Percutaneous Coronary Intervention With Drug-Eluting Stents in Asia. Circulation 118: 2730-2737 [Full Text]  
• Ostovan, M. A, Mollazadeh, R., Kojuri, J., Mirabadi, M. (2008). Experience with Paclitaxel-Eluting Infinnium Coronary Stents. Asian Cardiovasc. Thorac. Ann. 16: 454-458 [Abstract] [Full Text]  
• Cruden, N. L M, Harding, S. A, Newby, D. E (2008). Coronary stent thrombosis in the perioperative period. BMJ 337: a2074-a2074 [Full Text]  
• Kelly, R. V., Gillespie, M. J., Cohen, M. G., McLaughlin, D. P., Magnus Ohman, E., Stouffer, G. A. (2008). The Contrast Media Iohexol Causes Vasoconstriction of the Proximal Left Anterior Descending Coronary Artery: Implications for Appropriate Stent Sizing. ANGIOLOGY 59: 574-580 [Abstract]  
• Wenaweser, P., Daemen, J., Zwahlen, M., van Domburg, R., Juni, P., Vaina, S., Hellige, G., Tsuchida, K., Morger, C., Boersma, E., Kukreja, N., Meier, B., Serruys, P. W., Windecker, S. (2008). Incidence and Correlates of Drug-Eluting Stent Thrombosis in Routine Clinical Practice: 4-Year Results From a Large 2-Institutional Cohort Study. J Am Coll Cardiol 52: 1134-1140 [Abstract] [Full Text]  
• Hassantash, S.-A., Bikdeli, B., Kalantarian, S., Sadeghian, M., Afshar, H. (2008). Pathophysiology of Aortocoronary Saphenous Vein Bypass Graft Disease. Asian Cardiovasc. Thorac. Ann. 16: 331-336 [Abstract] [Full Text]  
• Holmes, D. R. Jr, Williams, D. O. (2008). Catheter-Based Treatment of Coronary Artery Disease: Past, Present, and Future. Circ Cardiovasc Intervent 1: 60-73 [Abstract] [Full Text]  
• Newsome, L. T., Kutcher, M. A., Royster, R. L. (2008). Coronary Artery Stents: Part I. Evolution of Percutaneous Coronary Intervention. Anesth. Analg. 107: 552-569 [Abstract] [Full Text]  
• Brugarolas, J., Lotan, Y., Watumull, L., Kabbani, W. (2008). Sirolimus in Metatastic Renal Cell Carcinoma. JCO 26: 3457-3460 [Full Text]  
• Bhatt, S. H, Hauser, T. H (2008). Very Late Stent Thrombosis After Dual Antiplatelet Therapy Discontinuation in a Patient with a History of Acute Stent Thrombosis. The Annals of Pharmacotherapy 42: 708-712 [Abstract] [Full Text]  
• Zellweger, M. J., Kaiser, C., Brunner-La Rocca, H. P., Buser, P. T., Osswald, S., Weiss, P., Mueller-Brand, J., Pfisterer, M. E., for the BASKET Investigators, (2008). Value and Limitations of Target-Vessel Ischemia in Predicting Late Clinical Events After Drug-Eluting Stent Implantation. JNM 49: 550-556 [Abstract] [Full Text]  
• Polyak, B., Fishbein, I., Chorny, M., Alferiev, I., Williams, D., Yellen, B., Friedman, G., Levy, R. J. (2008). High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents. Proc. Natl. Acad. Sci. USA 105: 698-703 [Abstract] [Full Text]  
• Padera, R. F. Jr., Schoen, F. J. (2008). Pathology of Cardiac Surgery. Card Surg Adult 3: 111-178 [Full Text]  
• Egashira, K., Nakano, K., Ohtani, K., Funakoshi, K., Zhao, G., Ihara, Y., Koga, J.-i., Kimura, S., Tominaga, R., Sunagawa, K. (2007). Local Delivery of Anti-Monocyte Chemoattractant Protein-1 by Gene-Eluting Stents Attenuates In-Stent Stenosis in Rabbits and Monkeys. Arterioscler. Thromb. Vasc. Bio. 27: 2563-2568 [Abstract] [Full Text]  
• Hlawaty, H., San Juan, A., Jacob, M.-P., Vranckx, R., Letourneur, D., Feldman, L. J. (2007). Inhibition of MMP-2 gene expression with small interfering RNA in rabbit vascular smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 293: H3593-H3601 [Abstract] [Full Text]  
• Xu, J., Ismat, F. A., Wang, T., Yang, J., Epstein, J. A. (2007). NF1 Regulates a Ras-Dependent Vascular Smooth Muscle Proliferative Injury Response. Circulation 116: 2148-2156 [Abstract] [Full Text]  
• Windecker, S., Meier, B. (2007). Late Coronary Stent Thrombosis. Circulation 116: 1952-1965 [Full Text]  
• Kereiakes, D. J., Teirstein, P. S., Sarembock, I. J., Holmes, D. R. Jr, Krucoff, M. W., O'Neill, W. W., Waksman, R., Williams, D. O., Popma, J. J., Buchbinder, M., Mehran, R., Meredith, I. T., Moses, J. W., Stone, G. W. (2007). The Truth and Consequences of the COURAGE Trial. J Am Coll Cardiol 50: 1598-1603 [Abstract] [Full Text]  
• Lee, B. H., Lee, J. E., Lee, K. W., Nam, H. Y., Jeon, H. J., Sung, Y. J., Kim, J. S., Lim, H. J., Park, J.-s., Ko, J. Y., Kim, D. J. (2007). Coating with paclitaxel improves graft survival in a porcine model of haemodialysis graft stenosis. Nephrol Dial Transplant 22: 2800-2804 [Abstract] [Full Text]  
• Chassot, P.-G., Delabays, A., Spahn, D. R. (2007). Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction. Br J Anaesth 99: 316-328 [Abstract] [Full Text]  
• Daemen, J., Serruys, P. W. (2007). Drug-Eluting Stent Update 2007: Part II: Unsettled Issues. Circulation 116: 961-968 [Full Text]  
• Fiorella, D., Woo, H. H. (2007). Emerging Endovascular Therapies for Symptomatic Intracranial Atherosclerotic Disease. Stroke 38: 2391-2396 [Full Text]  
• Holmes, D. R. Jr, Kereiakes, D. J., Laskey, W. K., Colombo, A., Ellis, S. G., Henry, T. D., Popma, J. J., Serruys, P. W.J.C., Kimura, T., Williams, D. O., Windecker, S., Krucoff, M. W. (2007). Thrombosis and Drug-Eluting Stents: An Objective Appraisal. J Am Coll Cardiol 50: 109-118 [Abstract] [Full Text]  
• Torella, D., Curcio, A., Gasparri, C., Galuppo, V., Serio, D. D., Surace, F. C., Cavaliere, A. L., Leone, A., Coppola, C., Ellison, G. M., Indolfi, C. (2007). Fludarabine prevents smooth muscle proliferation in vitro and neointimal hyperplasia in vivo through specific inhibition of STAT-1 activation. Am. J. Physiol. Heart Circ. Physiol. 292: H2935-H2943 [Abstract] [Full Text]  
• Verheye, S., Martinet, W., Kockx, M. M., Knaapen, M. W.M., Salu, K., Timmermans, J.-P., Ellis, J. T., Kilpatrick, D. L., De Meyer, G. R.Y. (2007). Selective Clearance of Macrophages in Atherosclerotic Plaques by Autophagy. J Am Coll Cardiol 49: 706-715 [Abstract] [Full Text]  
• Kereiakes, D. J. (2007). Does Clopidogrel Each Day Keep Stent Thrombosis Away?. JAMA 297: 209-211 [Full Text]  
• Meier, P., Zbinden, R., Togni, M., Wenaweser, P., Windecker, S., Meier, B., Seiler, C. (2007). Coronary Collateral Function Long After Drug-Eluting Stent Implantation. J Am Coll Cardiol 49: 15-20 [Abstract] [Full Text]  
• Pfisterer, M., Brunner-La Rocca, H. P., Buser, P. T., Rickenbacher, P., Hunziker, P., Mueller, C., Jeger, R., Bader, F., Osswald, S., Kaiser, C., for the BASKET-LATE Investigators, (2006). Late Clinical Events After Clopidogrel Discontinuation May Limit the Benefit of Drug-Eluting Stents: An Observational Study of Drug-Eluting Versus Bare-Metal Stents. J Am Coll Cardiol 48: 2584-2591 [Abstract] [Full Text]  
• Kimmelstiel, C. (2006). Multislice Computed Tomography After Left Main Drug-Eluting Stenting: Are We Putting the CarT Before the Horse?. Circulation 114: 616-619 [Full Text]  
• Spahn, D. R., Howell, S. J., Delabays, A., Chassot, P.-G. (2006). Coronary stents and perioperative anti-platelet regimen: dilemma of bleeding and stent thrombosis.. Br J Anaesth 96: 675-677 [Full Text]  
• Rogers, C., Edelman, E. R. (2006). Pushing Drug-Eluting Stents Into Uncharted Territory: Simpler Than You Think--More Complex Than You Imagine. Circulation 113: 2262-2265 [Full Text]  
• Silverman, M. E., Kounis, N. G., Kounis, G. N., Kouni, S. N., Taggart, D. P., Serruys, P. W., Ong, A. T.L. (2006). Coronary-artery stents.. NEJM 354: 2076-2078 [Full Text]