The treatment of head and neck cancer is complex and difficult,both technically and physically. Tumors in each site in thehead and neck (oropharynx, hypopharynx, larynx, and oral cavity)have the same squamous tissue and biologic features, but theirclinical presentation and responses to therapy differ accordingto site. In addition to this level of complexity, there is theinescapable fact that structures of the head and neck controlessential, continuously operational functions: speech, swallowing,eating, and breathing. This fact means that the short-term andlong-term side effects of treatment can profoundly affect thequality of life.
From the Division of Adult Oncology, DanaFarber Cancer Institute; the Department of Medicine, Brigham and Women's Hospital; and Harvard Medical School all in Boston.
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