There are many therapies that reduce the risk of fracture inpeople with osteoporosis. Calcium and vitamin D are the mostwidely used therapies for osteoporosis, even though their efficacyin terms of the prevention of fracture is uncertain. In fact,calcium supplements are the biggest seller in the multibillion-dollardietary-supplement industry; annual sales in the United Statesin 2004 have been estimated to be as high as $993 million.1
The effect of calcium supplementation on bone mineral densityhas been the subject of many studies. In general, calcium hasa small beneficial effect on bone mineral density, but it . . . [Full Text of this Article]
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From the Endocrine Unit, Department of Medicine, Massachusetts General Hospital, Boston.
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