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Correspondence
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Volume 354:769-771 February 16, 2006 Number 7
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Basal-Cell Carcinoma

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 by Rubin, A. I.
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To the Editor: The excellent review by Rubin et al. of basal-cell carcinoma (Nov. 24 issue)1 considers the genital area an unusual site for basal-cell carcinomas. In our view, this site, especially the vulva, is neither unusual nor random. Like melanoma,2 even basal-cell carcinomas appear in sun-shielded areas such as the vulva, challenging the conventional knowledge that associates these cancers with ultraviolet radiation.

Vulvar basal-cell carcinoma typically includes poor pigmentation and, often, a clinical appearance that mimics eczema or psoriasis.3 The dominant symptom, itching, often induces both patients and doctors to dismiss the condition as a simple irritation or intertrigo. . . . [Full Text of this Article]


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