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Volume 355:1067 September 7, 2006 Number 10
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Panic Disorder

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by Katon, W. J.
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To the Editor: Missing from Katon's review of panic disorder (June 1 issue)1 is the frequent correlation of symptoms with acute respiratory alkalosis resulting from hyperventilation. Table 1 of the article, showing criteria for the diagnosis of panic disorder, lists 13 symptoms, all of them common in the hyperventilation syndrome.2 Many patients with this syndrome are referred for a cardiac or neurologic workup before the correct diagnosis is made. Good symptomatic relief may be obtained with the use of a simple three-step approach. First, provide an elementary explanation of the carbon dioxide depletion consequent to overbreathing and the symptoms that . . . [Full Text of this Article]



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