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Volume 355:1178 September 14, 2006 Number 11
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Idiopathic Short Stature

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by Lee, M. M.
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To the Editor: The clinical vignette provided by Lee (June 15 issue)1 raises some issues that require clarification. The vignette does not include data on growth velocity or levels of insulin-like growth factor I and insulin-like growth factor–binding protein 3. I agree that the patient seems to have constitutional delay of growth and familial short stature and that no intervention is needed. Children with these conditions have normal growth velocities and achieve a normal adult height with respect to that of their family.2 The diagnosis of idiopathic short stature is not intended to include "normal-variant short stature." Growth rates that . . . [Full Text of this Article]



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