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FOCUS ON RESEARCH Previous Volume 355:1303-1305 September 28, 2006 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In 2002, as mosquitoes carried West Nile virus across the United States, infecting 4200 people, 23 confirmed cases of transfusion-transmitted infection and 7 related deaths were reported.¹ This was a dramatic demonstration that an emerging agent can threaten the safety of the blood supply. Because the virus's incubation period is usually 3 to 15 days and transmission by transfusion stood out against the background of a mosquito-borne epidemic, these transmissions were recognized quickly, nucleic acid–amplification technology was adapted for the detection of the virus, and the Food and Drug Administration (FDA) and Health Canada mandated the screening of donated blood . . . [Full Text of this Article]

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Dr. Blajchman is a professor of pathology and molecular medicine at McMaster University, head of transfusion medicine services at the McMaster–Hamilton Regional Laboratory Medicine Program, and medical director of the Hamilton Centre Canadian Blood Services — all in Hamilton, ON, Canada. Dr. Vamvakas is an adjunct professor of pathology and laboratory medicine at the University of Ottawa Faculty of Medicine, Ottawa.

Related Letters:

Transmission of Human Herpesvirus 8 by Blood Transfusion
Parisi S. G., Cruciani M., Palù G., Moore P. S., Chang Y., Jaffe H. W., Black H. J., Johnston A. M., Dollard S., Pellett P., Hladik W., Blajchman M. A., Vamvakas E. C.
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N Engl J Med 2007; 356:87-89, Jan 4, 2007. Correspondence

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