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Previous Volume 355:1466-1473 October 5, 2006 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A previously healthy 18-year-old college freshman presented to an emergency department with acute onset of fever and headache. He was listless and in distress. His temperature was 40.0°C, his pulse was 140 per minute, his blood pressure was 70/40 mm Hg, and his respirations were 35 per minute. Petechiae were noted over his thorax. Meningococcal septicemia was suspected (and subsequently confirmed by . . . [Full Text of this Article]

The Clinical Problem

Epidemiology of Neisseria meningitidis

Strategies and Evidence

Antimicrobial Chemoprophylaxis

Meningococcal Vaccines

Areas of Uncertainty

Guidelines

Conclusions and Recommendations

Source Information

From the Department of Medicine and the Graduate Program in Public Health, Stony Brook University School of Medicine, Stony Brook, NY.

Related Letters:

Prevention of Meningococcal Disease
Booy R., Iskander M., Viner R., Senanayake S. N., Gardner P.
Extract | Full Text | PDF  
N Engl J Med 2007; 356:524-526, Feb 1, 2007. Correspondence

This article has been cited by other articles:

• Davis, B. T., Pasternack, M. S. (2007). Case 19-2007 -- A 19-Year-Old College Student with Fever and Joint Pain. NEJM 356: 2631-2637 [Full Text]  
• Booy, R., Iskander, M., Viner, R., Senanayake, S. N., Gardner, P. (2007). Prevention of Meningococcal Disease. NEJM 356: 524-526 [Full Text]