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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.
A 69-year-old man undergoes a follow-up evaluation after testing showed an elevated serum prostate-specific antigen (PSA) level. One year previously, he had requested serum PSA testing after receiving counseling regarding its advantages and disadvantages. His serum PSA level at
The Clinical Problem
Pathophysiology and Effect of Therapy
Clinical Evidence
Clinical Use
Adverse Effects
Areas of Uncertainty
Guidelines
Recommendations
Source Information
From the Department of Radiation Oncology, Mayo Clinic, Rochester, MN.
Address reprint requests to Dr. Pisansky at the Department of Radiation Oncology, Mayo Clinic, 200 First St. SW, Rochester, MN 55905.
Related Letters:
Radiotherapy for Prostate Cancer
Rutz H. P., Lomax A. J., Campo A., Elconin J. H., Pisansky T. M.
Extract |
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N Engl J Med 2007;
356:308-311, Jan 18, 2007.
Correspondence
This article has been cited by other articles:
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