In our increasingly sedentary society, the rates of overnutrition,the metabolic syndrome, and frank diabetes mellitus are risingat an alarming rate.1 Once diabetes has developed, the risksof cardiovascular and renal disease are markedly increased.2Given the immense costs of diabetes both personal andeconomic considerable attention has been focused onidentifying effective strategies to prevent or delay its onsetin people at high risk.
The benefits of diet and exercise in reducing the risk of diabetesare well accepted. Numerous observational studies have documentedthat both adiposity and physical inactivity are strong independentrisk factors for . . . [Full Text of this Article]
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This editorial was published at www.nejm.org on September 15, 2006.
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