FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

FOCUS ON RESEARCH Previous Volume 355:1643-1645 October 19, 2006 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Bussel, J. B. PubMed Citation

Immune thrombocytopenic purpura (ITP) in adults is usually a chronic disease in which a low platelet count often causes mucocutaneous bleeding. ITP is a diagnosis of exclusion. Pseudothrombocytopenia and such disorders as drug-induced thrombocytopenia, microangiopathic thrombocytopenia, bone marrow failure, and congenital thrombocytopenia must be ruled out. The disorder can be primary (idiopathic) or secondary. Secondary ITP is associated with systemic lupus erythematosus, chronic lymphocytic leukemia, lymphoma, HIV infection or full-blown AIDS, hepatitis C infection, and a variety of other disorders.

Multiple mechanisms cause the thrombocytopenia in ITP, so the disorder is likely to be heterogeneous.¹ Over 50 years ago, Harrington . . . [Full Text of this Article]

Source Information

Dr. Bromberg is an associate professor of medicine and pharmacology at Temple University School of Medicine, Philadelphia.

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.