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Dr. Christine M. Cserti: A 3-year-old girl was admitted to this hospital because of fever and parasites in the peripheral blood.
Three weeks earlier, the patient and her 5-year-old brother and mother had traveled to Nigeria to visit relatives. Antimalarial chemoprophylaxis had been prescribed for the patient's mother but not for the children. They stayed in an urban hotel, were not near standing water, did not travel in the countryside, and did not recall any mosquito bites. When they returned to the United States, 5 days before admission, fever, rigors, lethargy, nausea, and vomiting developed in both children. The patient
Differential Diagnosis
Discussion of Management
Antimalarial Prophylaxis
Treatment of P. falciparum Malaria
Severe Malaria and Exchange Transfusion
Anatomical Diagnosis
Source Information
From the Department of Pediatrics (I.P.F.) and the Blood Transfusion Service (C.M.C., W.H.D.), Massachusetts General Hospital; and the Departments of Pediatrics (I.P.F.) and Pathology (C.M.C., W.H.D.), Harvard Medical School.
Related Letters:
Case 32-2006: A Girl with Fever after a Visit to Africa
Williams J., Agarwal R., Srinivas R., Nath A., Blazes D. L., Sanders J. W., Riddle M. S., Pasvol G., Fraser I. P., Cserti C. M., Dzik W. H.
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N Engl J Med 2007;
356:527-529, Feb 1, 2007.
Correspondence
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