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Editorial
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Volume 355:1724-1726 October 19, 2006 Number 16
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Aging and Fountain-of-Youth Hormones
Paul M. Stewart, M.D.

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-PubMed Citation
The search for eternal youth is vibrant in North America. In this search, it is all too easy to ascribe the aging process to endocrines. Although the secretion of growth hormone falls by about 12% per decade after middle age, perhaps the greatest attention has focused on sex steroids, since estrogen secretion falls abruptly in postmenopausal women, and testosterone levels decline with age, though more gradually, in men1,2 (Figure 1A). Levels of the adrenal sex steroid dehydroepiandrosterone (DHEA) and its sulfate ester fall progressively after 30 years of age, and after 60 years of age are less than . . . [Full Text of this Article]


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From the University of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom.


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