The search for eternal youth is vibrant in North America. Inthis search, it is all too easy to ascribe the aging processto endocrines. Although the secretion of growth hormone fallsby about 12% per decade after middle age, perhaps the greatestattention has focused on sex steroids, since estrogen secretionfalls abruptly in postmenopausal women, and testosterone levelsdecline with age, though more gradually, in men1,2 (Figure 1A).Levels of the adrenal sex steroid dehydroepiandrosterone (DHEA)and its sulfate ester fall progressively after 30 years of age,and after 60 years of age are less than . . . [Full Text of this Article]
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From the University of Birmingham, Queen Elizabeth Hospital, Edgbaston, Birmingham, United Kingdom.
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