Despite advances in medical knowledge, imaging techniques, andsurgical interventions, spinal epidural abscess remains a challengingproblem that often eludes diagnosis and receives suboptimaltreatment. The incidence of this disease two decadesago diagnosed in approximately 1 of 20,000 hospital admissions1 has doubled in the past two decades, owing to an agingpopulation, increasing use of spinal instrumentation and vascularaccess, and the spread of injection-drug use.2,3,4,5 Still,spinal epidural abscess remains rare: the medical literaturecontains only 24 reported series of at least 20 cases each.1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24This review addresses the pathogenesis, clinical features, diagnosis,treatment, common diagnostic . . . [Full Text of this Article]
Pathogenesis
Clinical Features
Diagnosis
Treatment
Diagnostic and Therapeutic Pitfalls
Outcome
Source Information
From the Infectious Disease Section, the Michael E. DeBakey Veterans Affairs Medical Center, and the Center for Prostheses Infection, Baylor College of Medicine, Houston.
Address reprint requests to Dr. Darouiche at the Center for Prostheses Infection, Baylor College of Medicine, 1333 Moursund Ave., Suite A221, Houston, TX 77030, or at rdarouiche@aol.com.
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Spinal Epidural Abscess
de Letona J. M. L., Gerstein N., Rigamonti D., Metellus P., Darouiche R. O.
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N Engl J Med 2007;
356:638-639, Feb 8, 2007.
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