The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Clinical Implications of Basic Research
PreviousPrevious
Volume 355:2042-2044 November 9, 2006 Number 19
NextNext

Connecting the Dots Using Gene-Expression Profiles
Steven R. Gullans, Ph.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
- PDF
-PDA Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited
-E-mail When Letters Appear

More Information
-PubMed Citation
Imagine you had a database of the gene-expression signatures of human diseases and their responses to therapeutic drugs. Its use could result in an unprecedented understanding of the interconnectivity of disease pathways and might also lead to the rational design of an optimal treatment or uncover new strategies for treating disease. Such a crystal ball does not yet exist, but a report by Lamb et al.1 offers a glimpse of this vision in a laboratory setting.

The traditional approach to developing new therapeutic drugs involves the painstaking identification of an individual drug target, such as a receptor or ion channel, . . . [Full Text of this Article]


Source Information

From RxGen, New Haven, CT.


This article has been cited by other articles:



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved.