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Previous Volume 355:192-194 July 13, 2006 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The RhD (Rh₀[D]) antigen is considered the most immunogenic of the antigens found on the surface of the human red cell. In 1941, Levine, Katzin, and Burham¹ showed that antibodies to the RhD antigen in pregnant women caused hemolysis and anemia in their offspring. Originally called erythroblastosis fetalis secondary to the finding of a large number of immature red cells in the neonatal circulation, today this condition is known as hemolytic disease of the fetus and newborn.

When RhD-positive fetal cells enter the maternal circulation as a result of pregnancy-related events such as miscarriage or delivery, anti-D antibody can . . . [Full Text of this Article]

Source Information

From the Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill.

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