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Previous Volume 355:212-213 July 13, 2006 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the case reported by Tamaki and Matsuoka (April 20 issue),¹ there is no definite evidence of human T-cell lymphotropic virus type I (HTLV-I) infection in the hematopoietic stem-cell donor, and there seems to be no clonality marker such as monoclonal proviral integration in the donor. We therefore cannot conclude that adult T-cell leukemia–lymphoma (ATL) in the recipient was instigated by undetected HTLV-I in the asymptomatic donor. The possibility of an acquired infection of donor T cells by HTLV-I in the recipient has not been excluded. We propose that the profound immunosuppression attributable to pretransplantation conditioning and . . . [Full Text of this Article]

Related Letters:

Donor-Derived T-Cell Leukemia after Bone Marrow Transplantation
Tamaki H., Matsuoka M.
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N Engl J Med 2006; 354:1758-1759, Apr 20, 2006. Correspondence

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