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Previous Volume 355:2132-2142 November 16, 2006 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

A 2-day-old boy was admitted to the special care nursery of this hospital because of hypotonia.

He was delivered at another hospital to a 40-year-old mother (gravida 2, para 2) at 38 weeks and 6 days of gestation by a scheduled cesarean section, which was the mother's second. The pregnancy was uneventful, and tests for rapid plasma reagin, hepatitis B surface antigen, and group B streptococcus were negative in the mother. Her blood type was A positive, with negative results on antibody screening, and she was immune to rubella. Fetal movements during the pregnancy were normal.

The delivery was uncomplicated, . . . [Full Text of this Article]

Differential Diagnosis

Abnormalities of the CNS and Peripheral Nervous System

The Neuromuscular Junction

Congenital Abnormalities of the Skeletal Muscle

Congenital Muscular Dystrophy

            Congenital Muscular Dystrophy with Markedly Abnormal CNS Development

            Congenital Muscular Dystrophy with Minimally Abnormal CNS Development

            Merosin-Deficient Congenital Muscular Dystrophy

Clinical Diagnosis

Dr. Robert H. Brown, Jr.'s Diagnosis

Pathological Discussion

Anatomical Diagnosis

Source Information

From the Departments of Neurology (R.H.B.) and Radiology (P.E.G.), Massachusetts General Hospital; the Department of Pathology, Children's Hospital (C.R.P.); and the Departments of Neurology (R.H.B.), Radiology (P.E.G.), and Pathology (C.R.P.), Harvard Medical School — all in Boston.

This article has been cited by other articles:

• Songstad, N. T., Klingenberg, C., Kaaresen, P. I., Brown, R. H. Jr. (2007). Case 35-2006: A Newborn Boy with Hypotonia. NEJM 356: 874-874 [Full Text]