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Case Records of the Massachusetts General Hospital
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Volume 355:2237-2245 November 23, 2006 Number 21
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Case 36-2006 — A 35-Year-Old Pregnant Woman with New Hypertension
Anne Klibanski, M.D., Antonia E. Stephen, M.D., Michael F. Greene, M.D., Michael A. Blake, M.D., and Chin-Lee Wu, M.D., Ph.D.

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Presentation of Case

Dr. Andrea L. Utz (Endocrinology): A 35-year-old pregnant woman (gravida 2, para 1) was admitted to this hospital at 19 weeks and 6 days of gestation because of the recent onset of hypertension and diabetes.

Three weeks before admission, at a routine prenatal visit, her blood pressure was 150/100 mm Hg. On the same day she saw her primary care physician, who recorded a blood pressure of 172/102 mm Hg. The results of a physical examination were normal. Urinalysis showed glucose (4+). The results of other laboratory tests are shown in Table 1. The next day, the blood pressure . . . [Full Text of this Article]

Differential Diagnosis

Hypertension in Pregnancy

Diabetes in Pregnancy

Cushing's Syndrome in Pregnancy

            Detecting Pathologically Excessive Cortisol Production

            Determining the Cause of Excess Cortisol Production

Dr. Anne Klibanski's Diagnosis

Pathological Discussion

Clinical Follow-up

Pathological Follow-up

Anatomical Diagnosis


Source Information

From the Neuroendocrine Unit (A.K.), the Department of Surgery (A.E.S.), the Obstetrics and Gynecology Service (M.F.G.), and the Departments of Radiology (M.A.B.) and Pathology (C.-L.W.), Massachusetts General Hospital; and the Departments of Medicine (A.K.), Surgery (A.E.S.), Obstetrics, Gynecology and Reproductive Biology (M.F.G.), Radiology (M.A.B.), and Pathology (C.-L.W.), Harvard Medical School.


Related Letters:

Case 36-2006: A Pregnant Woman with New Hypertension
Lindheimer M. D., Khurana A., Vinayek N., Stratakis C. A., Klibanski A., Greene M. F.
Extract | Full Text | PDF  
N Engl J Med 2007; 356:966-968, Mar 1, 2007. Correspondence

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