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Case Records of the Massachusetts General Hospital
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Volume 355:2349-2357 November 30, 2006 Number 22
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Case 37-2006 — A 19-Year-Old Woman with Thyroid Cancer and Lower Gastrointestinal Bleeding
Daniel C. Chung, M.D., Michael M. Maher, M.D., and William C. Faquin, M.D., Ph.D.

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Presentation of Case

A 19-year-old woman was seen in the outpatient gastroenterology division because of painless rectal bleeding.

The patient had been well until 8 months earlier, when a diagnosis of papillary carcinoma was made on examination of a biopsy specimen of a thyroid nodule obtained by fine-needle aspiration. A total thyroidectomy was performed, and pathological examination of the specimen disclosed a papillary thyroid carcinoma, cribriform–morular variant, with no involvement of the lymph nodes. Staging studies revealed no evidence of distant metastases. The patient was treated with a single, intravenously administered dose of radioactive iodine (iodine-131, 75 mCi), and follow-up studies showed no . . . [Full Text of this Article]

Differential Diagnosis

Non-Neoplastic Disorders

Neoplasms

Thyroid Cancer

Summary

Dr. Daniel C. Chung's Diagnosis

Pathological Discussion

Discussion of Management

Familial Adenomatous Polyposis: General Features and Clinical Management

Genetic Features and Genetic Testing

Anatomical Diagnosis


Source Information

From the Departments of Medicine (D.C.C.), Radiology (M.M.M.), and Pathology (W.C.F.), Massachusetts General Hospital and Harvard Medical School.



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