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A 68-year-old woman with severe postmenopausal osteoporosis was referred because of a 6-month history of erosive mucositis of the hard palate, accompanied by intense pain and dysphagia. The patient had an edentulous superior arch and wore a removable upper denture. Examination showed a large oval ulceration of the hard palate, 2 by 3 cm in diameter, with regular margins and a necrotic center (Panel A). Previous unsuccessful treatment of the lesion included systemic and topical corticosteroids, antibiotic agents, and antimycotic agents. Cytodiagnostic and microbiologic evaluations, including those for cancer, herpesviruses, and Treponema pallidum, were unrevealing. The patient did not report . . . [Full Text of this Article] |
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