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Clinical and translational research has all the right material for great stories. Heroines and heroes strive for truth and fame and fortune. The foe, whether disease, death, or suffering, gives urgency to these quests. Yet there are myriad obstacles to success, including false paths, competition, and sometimes enormous costs, including, most critically, the human costs sometimes paid by the participants in research. While stories of success in such pursuits tend to be celebrated in the pages of professional journals and textbooks, in classrooms, and sometimes in the popular media, stories of failure may find even broader reach, whether journalistic or
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