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A 19-year-old man presented with a 10-month history of Raynaud's phenomenon, fever, abdominal pain, and hypertension. On examination, he had multiple subcutaneous nodules on his forehead, and his blood pressure was 150/100 mm Hg. Laboratory findings included a normal urine sediment, an elevated erythrocyte sedimentation rate, mild anemia, and leukocytosis, with negative tests for antineutrophil cytoplasmic autoantibody, hepatitis B surface antigen, and hepatitis C antibody. Angiography revealed multiple microaneurysms involving the parenchymal branches of the hepatic artery, splenic artery, renal artery (Panel A, arrows), and superior mesenteric artery (Panel B, arrows). Biopsy of a subcutaneous nodule revealed necrotizing inflammation of . . . [Full Text of this Article] |
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