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Previous Volume 355:2591-2594 December 14, 2006 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The events of the phase 1 trial of TGN1412, as detailed by Suntharalingam et al. (Sept. 7 issue),¹ are a sobering reminder of the risks that research volunteers take when they participate in trials, but the article did not contain any comments on the subjects' mental state as they emerged from this near-death experience. The volunteers did not just suffer insults to kidney and pulmonary function; they were afflicted emotionally and perhaps intellectually as well. When an experimental drug has such serious adverse effects, it is worth reporting the psychological effects, which inform the ethical impact of . . . [Full Text of this Article]

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