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Previous Volume 355:2691-2693 December 21, 2006 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In this issue of the Journal, Heyland et al., writing for the Canadian Critical Care Trials Group, report the results of a multicenter, randomized trial comparing the use of bronchoalveolar lavage and endotracheal aspiration for the diagnosis of ventilator-associated pneumonia.¹ This study was part of a larger 2-by-2 factorial design also comparing empirical antimicrobial monotherapy (a carbapenem) and combination therapy (a carbapenem plus a fluoroquinolone). The authors conclude that bronchoalveolar lavage and endotracheal aspiration are associated with similar clinical outcomes and similar overall use of antibiotics. However, several important limitations of the study must be appreciated in order to place . . . [Full Text of this Article]

Source Information

From the Pulmonary and Critical Care Division, Washington University School of Medicine; and Medical Critical Care and Respiratory Care Services, Barnes–Jewish Hospital — both in St. Louis.

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• Osborne, M. (2007). Update in Critical Care. ANN INTERN MED 147: 412-416 [Full Text]  
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